Researchers at Augusta University in the US have found that a high-dose, two-week course of CBD can help restore brain function in Alzheimer’s sufferers.
According to Knowridge Science Report, the team discovered the treatment regime helped restore the function of two proteins key to reducing the accumulation of beta-amyloid plaque, a hallmark of Alzheimer’s disease, and improves cognition.
The proteins TREM2 and IL-33 help the brain’s immune cells consume dead cells and the beta-amyloid plaque that build up in patients’ brains. Levels of both are decreased in Alzheimer’s.
The team found CBD treatment increased levels of IL-33 by sevenfold and TREM2 by tenfold. Next steps include determining optimal doses and giving CBD earlier in the disease process.
They also reported that CBD normalises function and improves cognition by reducing levels of the immune protein IL-6, which is linked to the high inflammation found in Alzheimer’s patients’ brains.
The study was published in the Journal of Alzheimer’s Disease.